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Food intake, particularly ingestion of carbohydrate-rich food, increases GLP-1 secretion, which promotes post-prandial insulin secretion, -cell proliferation, and glucose homeostasis, contributing to reducing glucose levels and aiding weight loss

Retatrutide may become the high-efficacy benchmark if Phase 3 and regulatory review support the early signal

These minimum thresholds represent the approximate calorie levels needed to obtain adequate protein, essential fatty acids, vitamins, and minerals from food

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